BDBM26193 2-Hydroxybenzoate, I::2-hydroxybenzoic acid::CHEMBL424::phenol derivative, 7::salicylic acid
SMILES OC(=O)c1ccccc1O
InChI Key InChIKey=YGSDEFSMJLZEOE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 26193
Affinity DataKi: 5.88E+3nMAssay Description:Binding affinity towards human serum albuminMore data for this Ligand-Target Pair
Affinity DataKi: 7.10E+3nM ΔG°: -7.02kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 7.10E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.12E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataKi: 7.40E+5nMAssay Description:Inhibition of human carbonic anhydrase 2 esterase activity by non-competitive Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+8nMAssay Description:Reversible inhibition of bovine xanthine oxidaseMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate incubated for 10 mins by ELISAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate incubated for 10 mins by ELISAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human recombinant COX1 expressed in Sf9 cell microsomes assessed as reduction in conversion of arachidonic acid to PGE2 incubated for 5...More data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+5nMAssay Description:Inhibition of human carbonic anhydrase 2 esterase activity by spectrophotometryMore data for this Ligand-Target Pair